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HealthBench

lastmod 2025-09-23created 2025-05-142 edits

OpenAI's new benchmark for evaluating AI in healthcare

About

  • OpenAI released HealthBench, a new benchmark for evaluating AI system performance in medical settings
  • Built with 262 physicians, medical experience from 60 countries, and 5,000 realistic health conversations; each conversation uses evaluation criteria (rubric) written by physicians
  • The criteria cover accuracy, context awareness, communication quality, completeness, etc., and a GPT-4.1-based grader model scores whether each criterion is met
  • The latest OpenAI models show real progress: 28% performance gain over earlier models, better cost-performance for small models, and improved worst-case performance (worst-of-n)
  • The full HealthBench, Consensus, and Hard sets are released as open source for researchers and developers, to contribute to future medical AI research and safety

Background

  • Evaluations are needed to maximize AGI's potential in healthcare, such as broadening access to health information, supporting clinicians, and strengthening community health rights
  • Existing medical evaluation sets suffered from a lack of realism, weak grounding in expert judgment, and little headroom for model improvement

Key features

  • 5,000 multi-turn, multilingual, challenging health conversation scenarios
  • Each response is graded with a custom evaluation rubric created by physicians
  • A total of 48,562 evaluation criteria make it possible to quantify a wide range of fine-grained model capabilities
  • Grading is done by an automated rubric evaluation system using GPT-4.1

HealthBench themes and evaluation axes

7 evaluation themes

  • Emergency referrals: whether emergencies are recognized and appropriate action is recommended
  • Expertise-tailored communication: whether terminology/detail is adjusted to the user's level
  • Responding under uncertainty: appropriateness of responses under uncertain information
  • Response depth: providing the right depth of information for the situation
  • Health data tasks: practical medical work such as documentation and knowledge support
  • Global health: ability to adapt to each country's resources/circumstances/language
  • Context seeking: ability to ask for needed context on its own

Evaluation axes (Axes)

  • Accuracy: whether it matches medical facts and scientific consensus
  • Context awareness: whether the response is adjusted to the user's background
  • Completeness: whether all necessary content is included
  • Communication quality: appropriateness of length, terminology, structure, and emphasis
  • Instruction following: whether the user's requested format and approach are followed

Real-world evaluation examples

Example 1 - A 70-year-old neighbor is unconscious but breathing
Includes calling emergency medical services, placing them in the recovery position, stating when to start CPR, etc.
Scored 71 out of 92 rubric points (77%) → provided excellent emergency response guidance
Example 2 - Quercetin's antiviral preventive effect
Clearly conveyed the lack of evidence, but lacked recommended dosage/clinical data and omitted side effects
Scored 1 out of 25 rubric points (4%) → expressed scientific uncertainty well but lacked completeness
Example 3 - Writing a cardiac rehabilitation progress note
Presented a structured template but omitted much of the key clinical information
Scored 15 out of 42 rubric points (36%)

Model performance comparison

Performance by model (overall/by theme/by axis)

  • o3 achieved the top performance (0.598) across all themes and evaluation axes
  • GPT-4.1, Claude 3.7, and Gemini 2.5 Pro follow
  • GPT-3.5 Turbo and Llama 4 scored markedly lower

Cost-performance

  • GPT-4.1 nano is 25x cheaper than GPT-4o yet performs better
  • Small models keep improving, showing that low-cost, high-performance is achievable

Reliability (worst-of-n performance)

  • o3 and GPT-4.1 also improved worst-case performance
  • An important metric for ensuring reliability in high-risk domains

Extended benchmarks: Consensus & Hard

  • HealthBench Consensus: high-reliability evaluation set designed around consensus criteria from multiple physicians (3,671 examples)
    • Error rate close to zero
  • HealthBench Hard: 1,000 difficult examples that even the latest models struggle with
    • Can be used as an evaluation set to test headroom for model improvement

Comparison with human physicians

  • AI model alone vs physicians (no reference) vs physicians (with access to model responses)
  • Against 2024 models: the physician + model combination outperformed the model alone
  • The latest 2025 models (o3, GPT‑4.1) match or exceed physician responses
    • Less room for further improvement

Evaluation reliability

  • High agreement between GPT-4.1 grading and actual physician grading
  • Model grading criteria align with physician judgment at a similar level → validates the automated rubric grading system

Future directions

  • All data and evaluation tools are released on GitHub at https://github.com/openai/simple-evals
  • Encourages continuous community-driven evaluation and improvement for meaningful AI progress in healthcare
  • Remaining challenges to solve include Context seeking and worst-case handling (Reliability)

See also

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